Detalhe da pesquisa
1.
Tryptophan residues in TDP-43 and SOD1 modulate the cross-seeding and toxicity of SOD1.
J Biol Chem
; 300(5): 107207, 2024 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38522514
2.
Testing the feasibility of targeting a conserved region on the S2 domain of the SARS-CoV-2 spike protein.
Biophys J
; 123(8): 992-1005, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38491772
3.
Cyclization Scaffolding for Improved Vaccine Immunogen Stability: Application to Tau Protein in Alzheimer's Disease.
J Chem Inf Model
; 64(6): 2035-2044, 2024 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38427576
4.
PROTHON: A Local Order Parameter-Based Method for Efficient Comparison of Protein Ensembles.
J Chem Inf Model
; 63(11): 3453-3461, 2023 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37178169
5.
TNF receptor-associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation.
J Biol Chem
; 295(12): 3808-3825, 2020 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32029478
6.
Passive immunotherapies targeting Aß and tau in Alzheimer's disease.
Neurobiol Dis
; 144: 105010, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32682954
7.
Soft Vibrational Modes Predict Breaking Events during Force-Induced Protein Unfolding.
Biophys J
; 114(3): 562-569, 2018 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29414701
8.
The unfolding mechanism of monomeric mutant SOD1 by simulated force spectroscopy.
Biochim Biophys Acta Proteins Proteom
; 1865(11 Pt B): 1631-1642, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28629863
9.
As Simple As Possible, but Not Simpler: Exploring the Fidelity of Coarse-Grained Protein Models for Simulated Force Spectroscopy.
PLoS Comput Biol
; 12(11): e1005211, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27898663
10.
Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms.
Proc Natl Acad Sci U S A
; 111(9): 3620-5, 2014 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550511
11.
SOD1 exhibits allosteric frustration to facilitate metal binding affinity.
Proc Natl Acad Sci U S A
; 110(10): 3871-6, 2013 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23431152
12.
Intermolecular transmission of superoxide dismutase 1 misfolding in living cells.
Proc Natl Acad Sci U S A
; 108(39): 16398-403, 2011 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-21930926
13.
De Novo Design of a ß-Helix Tau Protein Scaffold: An Oligomer-Selective Vaccine Immunogen Candidate for Alzheimer's Disease.
ACS Chem Neurosci
; 14(15): 2603-2617, 2023 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37458595
14.
Ensemble Generation for Linear and Cyclic Peptides Using a Reservoir Replica Exchange Molecular Dynamics Implementation in GROMACS.
J Phys Chem B
; 126(49): 10384-10399, 2022 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36410027
15.
First Principles Calculation of Protein-Protein Dimer Affinities of ALS-Associated SOD1 Mutants.
Front Mol Biosci
; 9: 845013, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35402516
16.
Misfolding-Associated Exposure of Natively Buried Residues in Mutant SOD1 Facilitates Binding to TRAF6.
J Mol Biol
; 434(16): 167697, 2022 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35753527
17.
Assessment of protein inclusions in cultured cells using automated image analysis.
STAR Protoc
; 3(4): 101748, 2022 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36201320
18.
Optimizing Epitope Conformational Ensembles Using α-Synuclein Cyclic Peptide "Glycindel" Scaffolds: A Customized Immunogen Method for Generating Oligomer-Selective Antibodies for Parkinson's Disease.
ACS Chem Neurosci
; 13(15): 2261-2280, 2022 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35840132
19.
Rational Generation of Monoclonal Antibodies Selective for Pathogenic Forms of Alpha-Synuclein.
Biomedicines
; 10(9)2022 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36140270
20.
A theory for the anisotropic and inhomogeneous dielectric properties of proteins.
Phys Chem Chem Phys
; 13(13): 6286-95, 2011 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21359369